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Laboratory Medicine

Test Directory / CSF Lactate

CSF Lactate

Fluoride Oxalate

TestCSF Lactate
Common AbbreviationsNA
Tube typefluoride EDTA
Clinical IndicationLactate levels in CSF will generally mirror levels in blood/plasma. However, increases in lactate CSF levels alone have been seen in bacterial meningitis and certain inborn errors of metabolism e.g. mitochondrial myopathies
Specimen TypeCSF
Sample typeCSF
Minimum Volume200µl
Special PrecautionsSpecimens received in plain universal tubes should be rapidly transferred into Fluoride Oxalate tubes
Stability3 hours at 15-25 °C, 24 hours at 2-8 °C, 2 months at (-15)- (-25) °C
Turnaround TimeInpatient: 4 hours Outpatient/ GP: 24 hours
LaboratoryYork and Scarborough
Reference Interval1.1 - 2.4 mmol/L
LimitationsN-Acetyl Cysteine (NAC) when administered in therapeutic concentrations (for the treatment of paracetamol overdose) may lead to falsely low results.
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