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Laboratory Medicine

Test Directory / Cystatin C (and CKD-EPI eGFR)

Cystatin C (and CKD-EPI eGFR)

Brown clotted serum, gel barrier or orange lithium heparin

TestCystatin C (and CKD-EPI eGFR)
Common AbbreviationsCYSC
ProfileNA
Tube typeBrown clotted serum, gel barrier or orange lithium heparin
Clinical IndicationThis test is available for Renal Consulants only. NICE GC182: Consider using eGFRcystatinC at initial diagnosis to confirm or rule out CKD in people with an eGFRcreatinine of 45–59 ml/min/1.73 m2, sustained for at least 90 days AND no proteinuria (albumin:creatinine ratio [ACR] less than 3 mg/mmol) or other marker of kidney disease. eGFRcystatinC is reported using the CKD-EPI equestion.
Specimen TypeBlood
Sample typeSerum
Minimum Volume0.25mL
Special PrecautionsNo special requirements
Stability7 days at 4'C once separate from cells
Turnaround TimeContact Referral Laboratory
LaboratoryDepartment of Clinical Biochemistry, Manchester University NHS Foundation Trust, M13 9WL. 0161 276 8766
Reference IntervalRefer to NICE CG 182
LimitationsInterpret eGFRcystatinC with caution in people with uncontrolled thyroid disease because eGFRcystatinC values may be falsely elevated in people with hypothyroidism and reduced in people with hyperthyroidism.
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