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Laboratory Medicine

Test Directory / Insulin-like Growth Factor 1

Insulin-like Growth Factor 1

Brown clotted serum, gel barrier or orange lithium heparin

TestInsulin-like Growth Factor 1
Common AbbreviationsIGF1
ProfileNA
Tube typeBrown clotted serum, gel barrier or orange lithium heparin
Clinical IndicationInsulin-like growth factor 1 (IGF1) measurement is useful in the evaluation of growth disorders and in the diagnosis and monitoring of pituitary disease.
Specimen TypeBlood
Sample typeSerum or plasma
Minimum Volume0.5mL If requesting more than 10 biochemistry tests please send an additional sample specifically for IGF1.
Special PrecautionsNo special requirements
Stability 24 hours at 15 - 25°C, 48 hours at 2 - 8°C and 28 days at -20°C
Turnaround Time Inpatient: 7 days Outpatient/GP: 7 days
LaboratoryYork
Reference IntervalPlease refer to reference ranges available: https://www.yorkhospitals.nhs.uk/our-services/a-z-of-services/lab-med/general-information/information-for-health-care-professionals1/advice-for-primary-or-secondary-care-clinical-biochemistry/
LimitationsAnalysis should not be performed on haemolysed, icteric or lipaemic samples. The assay is unaffected by biotin (< 205 nmol/L or < 50 ng/mL) No interference was observed from rheumatoid factors up to a concentration of 1200 IU/mL. No interference was observed from IgG < or equal to 3.3 g/dL; IgA < or equal to 0.5 g/dL; IgM < or equal to 1.0 g/dL Samples should not be taken from patients receiving therapy with high biotin doses (i.e. > 5 mg/day) until at least 8 hours following the last biotin administration. In vitro tests were performed on 16 commonly used pharmaceuticals. No interference with the assay was found. In addition, special growth disorder drugs were tested. No interference was found. In rare cases, interference due to extremely high titres of antibodies to analyte specific antibodies, streptavidin or ruthenium can occur. These effects are minimized by suitable test design.
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Invitation to attend the Trust’s Annual Members Meeting

Trust members and the general public are invited to find out more about their local hospitals by attending the Trust’s virtual Annual Members Meeting (AMM), incorporating the Annual General Meeting (AGM), on Tuesday 26 October 2021, between 11:00am-12:30pm.