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Laboratory Medicine

Test Directory / Thiopurine Methyl Transferase

Thiopurine Methyl Transferase


TestThiopurine Methyl Transferase
Common AbbreviationsTPMT
Tube typeEDTA
Clinical IndicationActivity of TPMT exhibits genetic polymorphism within 1 in 10 caucasians having reduced activity. These patients are at risk of haematopoietic toxicity, myelosuppression and even death. Measuring TPMT activity enables appropriate dosing.
Specimen TypeBlood
Sample typeEDTA whole blood
Minimum Volume4mL
Special PrecautionsNo special requirements
StabilityContact Referral Laboratory
Turnaround Time1 working day
LaboratoryCity Hospital Birmingham B18 7QH 0121 507 5345
Reference IntervalContact Referral Laboratory
LimitationsContact Referral Laboratory
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