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Laboratory Medicine

Test Directory / Urine Osmolality

Urine Osmolality

Urine monovette or white topped universal (no additives)

TestUrine Osmolality
Common AbbreviationsUOSM
Tube typeUrine monovette or white topped universal (no additives)
Clinical IndicationDetermination of serum and urine osmolality can be useful in the assessment of electrolyte and acid-base disorders. Comparison of serum and urine osmolalities can determine the status of renal water regulation in settings of severe electrolyte disturbances as might occur in diabetes insipidus or the syndrome of inappropriate anti-diuretic hormone. Osmolality may also be performed as part of a water deprivation test (used in the diagnosis of diabetes insipidus) or where there is suspicion of ingestion of an osmotically active substance such as ethanol, methanol or ethylene glycol.
Specimen TypeUrine
Sample typeRandom Urine
Minimum Volume1mL
Special PrecautionsNo special requirements
Stability5 days at room temperature, 4 days at 4°C and ? 14 days at -20°C
Turnaround TimeInpatient: 24 hours Outpatient/ GP: 24 hours
LaboratoryYork and Scarborough
Reference Interval300-900 mOsm/kg
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