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Research and Development

Research has led to better treatments for many conditions such as cancer, diabetes and stroke. We also have a better understanding of why some people get certain health problems. Research has improved the accuracy of some of the tests we use to see if someone has a condition or not. It has also given us a better idea of what it is like to live with particular health problems. All of this new knowledge helps us to develop services and provide better advice, support and treatment.

The development of new treatments and medical devices can take a long time, so often taking part in research is to help future generations, not just yourself

There is a continuing need to keep research going as our population is growing and we are now living longer which means many of us are suffering from more than one medical problem at a time (co morbidities)

Research can take many forms; clinical trials are not the only way research happens. For example, just being interviewed about your condition, by a researcher, can help them really understand your condition, and what you’d like to happen to make things easier for you, this is called Qualitative Research. Other ways you can participate in research is to allow researchers access to your images or tissue, so they can investigate the workings of the human body easily. Finally, looking at anonomised data, from such things as lab results and hospital admissions can help us understand links and causation that sometimes would go un-noticed.

Some of our research highlights from this year have been:

  • Anaesthesia, Periop Medicine and Pain Specialty Group which now sees York Hospital recruit 25% of the total number of patients in clinical trials in England. For example we were the highest recruiters in the region for the PROBESE trial. The trial is aimed at studying protective Ventilation during general anaesthesia for surgery obese patients.

  • Ophthalmology where we were the highest recruiters in the UK for a study called SAFARI that reviewed drugs in patients with Age related macular degeneration

  • Cardiology where we recruited the first UK patient in a clinical trial called ARIADNE which was looking at new drugs for patients with heart failure

  • We recruited 150 patients into a clinical trial called PRIDE that was aimed at looking at micronutrients in the blood of pregnant women at risk of gestational diabetes and over 100 patients into a trial called VESPA looking at scanning in ladies in the early stage of pregnancy

  • Our haematology/ oncology team for being the highest recruiters in the region for the Facilitating Informed Decision Making in Haemato-Oncology (FIDO) trial, so far the team have recruited over 400 patients to this trial. The trial is aimed at how patients make decisions about their care with questionnaires before and after clinical appointments

  • We were also the top recruiters in the UK a Rheumatology study that was following patients with Rheumatoid Arthritis given immunosuppressant drugs for the first time

  • Our hospital is also part of the Yorkshire Health Study which is a questionnaire style study and so far we have recruited over 700 patients

We are proud to be a partner with the Hull York Medical School (HYMS) in providing clinical placements and training for future doctors at Scarborough and York Hospitals.  As a Teaching hospital our researchers and academics have a strong track record of clinical and research excellence across the majority of our clinical directorates. 

What research takes place within the Trust 

From 1st April 2016 to 31st March 2017 our Trust had 147 research studies open to recruitment in York and Scarborough, which resulted in 4588 patients being recruited into clinical trials.

We are currently research active in the following clinical areas but we are always on the lookout to develop research in new areas;

Anesthetic Cardilogy Dermatology Diabetes
Gastro Haematology Microbiology Obs & Gynae
Oncology Ophthalmology Orthopaedics Paediatrics
Renal Respiratory Rheumatolog Sexual Health

Some of the projects are taking place throughout the UK. Others just involve York and Scarborough and perhaps our neighbouring NHS trusts.  All research projects have to have certain approvals before they can begin.

How can you get involved in research?

Patient Research Ambassador

We are always looking to recruit Patient Research Ambassadors to join our team. A Patient Research Ambassador is someone who promotes health research from a patient point of view. They could be a patient, service user, carer or lay person who is enthusiastic about health research and willing to communicate that to other patients and public as well as healthcare professionals.

The role is supported by the National Institute for Heath Research and national information and can be found here.

Local information on the role can be found here.

In our hospital we work with our Patient Research Ambassadors to promote our work and encourage others to take part. For example, we host stands that informs people what research we do, and how to get involved.  We ensure that all our Patient Research Ambassadors are supported by our Patient Volunteer Network and are fully briefed on research by the Research & Development Office before they undertake the role. 

Lay Review panel

We have recently trained a small group of interested members and governors into the background of clinical research so they can now read patient facing research materials for us, and edit them to be more understandable to the public. We fully support this small group and offer full background and briefings on clinical research before they start this role.

If you would be interested in finding out more about these roles or in applying to get involved in our research please contact

Lydia Harris

Would you like more information

If you would like to find out more about clinical research in our hospital please contact

Research & Development
York Hospital
Wigginton Road
YO31 8HE
01904 726996

Search for a clinical trial

The UK Clinical Trials Gateway provides easy to understand information about clinical research trials running in the UK, and gives you and others access to a large range of information about these trials. It is designed to enable you and your clinician to locate and contact trials of interest to you.

To find a clinical trial in your area simply search for a condition or disease and add 'York'.


York Teaching Hospital NHS Foundation Trust, like other NHS providers holding NIHR contracts, is required to provide quarterly performance reports to the NIHR Central Commissioning Facility.

These reports provide an overview of recruitment to clinical trials, including commercial contract clinical trials.  They show whether the Trust has met the ’70 day benchmark’ of recruiting a patient into a trial within 70 days of receiving a valid application for approval to open the study.

The reports for the third and fourth quarters of 2014/15, the first, second, third and fourth quarters of 2015/16, the first, second, third and fourth quarters of 2016/17 and the first, second and third quarters of 2017/18 can be found below.





For more information about these reports or any of the studies, please contact the R&D Unit.

Last year just under 3,000 people took part in research projects at York Hospital and just over 550 at Scarborough Hospital

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Patients Know Best

York and Scarborough Teaching Hospitals NHS Foundation Trust is now offering patients the opportunity to sign up to our new online service that gives you secure access to your health record from any smartphone, tablet or computer. It’s designed to improve your patient experience and access to NHS services and information. The service is provided in partnership with Patients Know Best (PKB).  Further information can be found on our website, including frequently asked questions.