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Laboratory Medicine

Test Directory / Alkaline Phosphatase Isoenzymes

Alkaline Phosphatase Isoenzymes

Brown clotted serum, gel barrier

TestAlkaline Phosphatase Isoenzymes
Common AbbreviationsALPI
Tube typeBrown clotted serum, gel barrier
Clinical IndicationALP originates in approximately equal proportions from the liver and skeletal system. Approximately 25% of healthy individuals also have intestinal ALP which accounts for 10% of the total ALP in a fasting specimen. Increases in total ALP are either due to physiological causes or are caused by diseases of the liver or bone. Physiological increases are found in pregnancy, in growing children, and post prandially in individuals with blood groups B and O. Separation allows for the identification of the ALP isoenzyme which is causing the increase in the total ALP.
Specimen TypeBlood
Sample typeSerum
Minimum Volume0.5mL If requesting more than 10 tests please send an additional brown clotted serum sample.
Special PrecautionsNo special requirements
Stability7 days at 2-25°C
Turnaround TimeInpatient: 2 weeks Outpatient/ GP: 2 weeks
Reference IntervalInterpretative result provided
LimitationsSevere haemolysis, jaundice or lipaemia may interfere.
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