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Laboratory Medicine

Test Directory / Carbamazepine

Carbamazepine

Brown clotted serum, gel barrier or orange lithium heparin

TestCarbamazepine
Common AbbreviationsCAR, CARB
ProfileNA
Tube typeBrown clotted serum, gel barrier or orange lithium heparin
Clinical IndicationCarbamazepine is an anticonvulsant drug, used in particular for the treatment of a variety of seizures, partial epilepsy and neuralgia. Effective serum concentrations of carbamazepine are essential for seizure control; however, serum concentrations show only a moderate correlation to dose. Co-administration of other anti-epileptic agents can significantly increase the effect of carbamazepine levels. Carbamazepine toxicity may or may not be dose related, however CNS symptoms such as vertigo, dizziness and diplopia are dose related with chronic therapy.
Specimen TypeBlood
Sample typeSerum
Minimum Volume0.5mL If requesting more than 10 tests please send an additional brown clotted serum sample.
Special PrecautionsNo special requirements
Stability5 days at 20-25°C and 7 days at 2-8°C
Turnaround TimeInpatient: 6 hours Outpatient/ GP: 24 hours
LaboratoryYork and Scarborough
Reference IntervalPre-dose sample: 4-12 mg/L (Recommended by Pathology Harmonisation Reference Group)
LimitationsSamples containing either antibodies to E. coli ?-galactosidase or human anti-mouse antibodies (HAMA) may result in artificially high results. The incidence of patients having such antibodies is extremely low.
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Invitation to attend the Trust’s Annual Members Meeting

Trust members and the general public are invited to find out more about their local hospitals by attending the Trust’s virtual Annual Members Meeting (AMM), incorporating the Annual General Meeting (AGM), on Tuesday 26 October 2021, between 11:00am-12:30pm.