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Laboratory Medicine

Test Directory / Creatinine

Creatinine

Brown clotted serum, gel barrier or lithium heparin

TestCreatinine
Common AbbreviationsCREA, CREAT
ProfileUrea and Electrolytes
Tube typeBrown clotted serum, gel barrier or lithium heparin
Clinical IndicationMeasurements of creatinine are used in the diagnosis and treatment of renal disease and are useful for the evaluation of glomerular function and in monitoring renal dialysis. The serum level is not sensitive to early damage and responds more slowly than urea to haemodialysis.
Specimen TypeBlood
Sample typeSerum
Minimum Volume0.5mL If requesting more than 10 tests please send an additional brown clotted serum sample.
Special PrecautionsNo special requirements
Stability7 days at 2-25°C
Turnaround TimeUrgent: 2 hours Inpatient: 4 hours Outpatient/ GP: 24 hours
LaboratoryYork and Scarborough
Reference IntervalAdult Females: 45-84 µmol/L, Adult Males: 59-104µmol/L, Neonates: 27-77 µmol/L, 1 month-1 year: 14-34 µmol/L, 1-3 years: 15-31µmol/L, 3- 5 years: 23-37µmol/L, 5-7 years: 25-42µmol/L, 7-9 years: 30-47µmol/L, 9-11 years: 29-56µmol/L, 11-13 years: 39-60µmol/L, 13-15 years: 40-68µmol/L (depends on muscle mass). New ranges as of 03/04/18.
LimitationsN-Acetyl Cysteine (NAC) when administered in therapeutic concentrations (for the treatment of paracetamol overdose) may lead to falsely low results. Calcium dobesilate, Methimazole, Dicynone, Rifampicin, Levodopa and Methyldopa can cause artificially low results. In very rare cases gammopathy, especially monoclonal IgM (Waldenström’s macroglobulinemia), may cause unreliable results. Advise people not to eat any meat in the 12 hours before having a blood test for creatinine (ingestion of cooked meat causes transient increases in blood creatinine).
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