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Laboratory Medicine

Test Directory / Faecal Elastase

Faecal Elastase

Faeces

TestFaecal Elastase
Common AbbreviationsFELA
ProfileNA
Tube typeFaeces
Clinical IndicationHuman pancreatic elastase 1 is a particularly resilient protein molecule that remains intact during intestinal transit. The concentration of this enzyme in faeces has been used as an indication of exocrine pancreatic function. The molecule is pancreas-specific and the concentration in faeces reflects the secretory capacity of the pancreas.
Specimen TypeFaeces
Sample typeFaeces extract
Minimum VolumeSingle spot stool sample
Special PrecautionsNo special requirements
Stability6 days at RT or 4-8°C and for longerperiods freeze.
Turnaround TimeInpatient: 7 days Outpatient/ GP: 7 days
LaboratoryYork
Reference IntervalElastase >200 µg/g No indication of exocrine pancreatic insufficiency. Elastase 100-199 µg/g Results consistent with exocrine pancreatic insufficiency. Elastase <100 µg/g Results consistent with severe exocrine pancreatic insufficiency
LimitationsWatery stools may show falsely low elastase results due to sample dilution, results should be interpreted with caution.
Notes
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