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Laboratory Medicine

Test Directory / Ferritin


Brown clotted serum, gel barrier

Common AbbreviationsFER
Tube typeBrown clotted serum, gel barrier
Clinical IndicationFerritin plays a significant role in the absorption, storage, and release of iron. Ferritin is found in the serum in low concentrations and is directly proportional to the body's iron stores. Serum ferritin concentration, when analysed with other factors such as serum transferrin saturation and tissue iron stores, is valuable in the diagnosis of iron deficiency anaemia, anaemia of chronic infection, thalassaemia and haemachromatosis. Measurement of serum ferritin is particularly valuable in distinguishing iron deficiency anaemias caused by low iron stores from those resulting from inadequate iron utilization.
Specimen TypeBlood
Sample typeSerum
Minimum Volume0.5mL If requesting more than 10 tests please send an additional brown clotted serum sample.
Special PrecautionsNo special requirements
Stability48 hours at 20 - 25°C, 7 days at 2 - 8°C and 12 months at -20°C
Turnaround TimeInpatient: 24 hours Outpatient/ GP: 24 hours
LaboratoryYork and Scarborough
Reference IntervalMale: 30 - 400 µg/L (Quoted by the manufacturer) Females < 60 years: 30 - 150 µg/L (Quoted by the manufacturer) Females > 60 years: 30 - 260 µg/L (Derived in-house)
LimitationsAnalysis should not be performed on haemolysed, icteric or lipaemic samples. The assay is unaffected by biotin < 205 nmol/L or < 50 ng/mL. No interference was observed from rheumatoid factors up to a concentration of 1200 IU/mL. Samples should not be taken from patients receiving therapy with high biotin doses (i.e. > 5 mg/day) until at least 8 hours following the last biotin administration. In rare cases, interference due to extremely high titers of antibodies to analyte specific antibodies, streptavidin or ruthenium can occur. In vitro tests were performed on 16 commonly used pharmaceuticals. No interference with the assay was found.
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