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Laboratory Medicine

Test Directory / Lactate Dehydrogenase

Lactate Dehydrogenase

Brown clotted serum, gel barrier or lithium heparin

TestLactate Dehydrogenase
Common AbbreviationsLDH
Tube typeBrown clotted serum, gel barrier or lithium heparin
Clinical IndicationThe main role of total LDH is in the detection of minor tissue damage. High specific activities of the enzyme are found in the liver, cardiac muscle, skeletal muscle, kidneys and erythrocytes. Myocardial infarction is associated with a 3-4 fold increase of total LDH. Elevations of LDH activity are observed in liver damage, particularly toxic hepatitis with jaundice. Other diseases that can cause increased LDH levels include duchenne muscular dystrophy, renal infarction and haemolytic and megaloblastic anaemias.
Specimen TypeBlood
Sample typeSerum or plasma
Minimum Volume0.5mL If requesting more than 10 tests please send an additional brown clotted serum sample.
Special PrecautionsNo special requirements
Stability4 days at 2-8°c and for 7 days at 15-25°c
Turnaround TimeInpatient: 4 hours Outpatient/ GP: 24 hours
LaboratoryYork and Scarborough
Reference IntervalNeonates (4-20 days): 225-600 U/L, Children (<15 years old): 120-300 IU/L, Adult females: 135-214 IU/L, Adult males: 135-225 IU/L
LimitationsIn vitro tests were performed on 16 commonly used pharmaceuticals. No interference with the assay was found. In addition, special growth disorder drugs were tested. No interference was found.
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