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Laboratory Medicine

Test Directory / Paracetamol

Paracetamol

Brown clotted serum, gel barrier or orange lithium heparin

TestParacetamol
Common AbbreviationsPAR , Acetaminophen
ProfileNA
Tube typeBrown clotted serum, gel barrier or orange lithium heparin
Clinical IndicationA mild non prescription analgesic used to treat pain and fever. Safe at recommended doses but when consumed in overdose quantities can cause severe hepatic toxicity and death. Measurment is often used in cases of suspected overdose to help guide further patient management. Early diagnosis of paracetamol overdose is important as initiation of specific therapy within 16 hours of ingestion reduces the risk of hepatic injury & decreases the rate of mortality.
Specimen TypeBlood
Sample typeSerum or plasma
Minimum Volume0.5mL If requesting more than 10 tests please send an additional brown clotted serum sample.
Special PrecautionsNo special requirements
Stability14 days at 2-8°C and 4 weeks at -20°C
Turnaround TimeUrgent: 2 hours Inpatient: 4 hours Outpatient/ GP: 24 hours
LaboratoryYork and Scarborough
Reference IntervalNot applicable to this assay
LimitationsAmitrypitilline, Amphetamine, Imipramine can cause >10% negative interference. N-acetyl cysteine treatment can cause falsely low results. NAPQI may cross react in the assay (>10%)
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