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Laboratory Medicine

Test Directory / Phenytoin

Phenytoin

Brown clotted serum, gel barrier or orange lithium heparin

TestPhenytoin
Common AbbreviationsEpanutin, PHT
ProfileNA
Tube typeBrown clotted serum, gel barrier or orange lithium heparin
Clinical IndicationPhenytoin is one of the most widely prescribed anti convulsant drugs for the treatment of epilepsy particularly grand mal epilepsy, cortical focal seizures and temporal lobe epilepsy. Measured to check therapeutic levels and compliance.
Specimen TypeBlood
Sample typeSerum or plasma
Minimum Volume0.5mL If requesting more than 10 tests please send an additional brown clotted serum sample.
Special PrecautionsNo special requirements
Stability4 days at 2-25C in capped samples
Turnaround TimeInpatient: 6 hours Outpatient/ GP: 24 hours
LaboratoryYork and Scarborough
Reference IntervalTherapeutic Range: 5-20 mg/L (Recommended by the Pathology Harmonisation Reference Group)
LimitationsSamples containing antibodies to E. coli ?-galactosidase may result in artificially high results which will not fit the clinical profile. The incidence of patients having such antibodies is extremely low. As with any assay employing mouse antibodies, the possibility exists for interference by human anti-mouse antibodies (HAMA) in the sample, which could cause falsely elevated results.
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