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Laboratory Medicine

Test Directory / Salicylate


Brown clotted serum, gel barrier

Common AbbreviationsSAL
Tube typeBrown clotted serum, gel barrier
Clinical IndicationMeasurement of salicylate is important in cases of suspected overdose to assess the severity of toxicity. It is important to be aware that toxic doses of salicylate may cause pylorospasm which results in delayed absorption. In such cases peak concentrations may not be reached for upto 6 hours. Acute overdose can cause nausea, vomiting, dehydration, hypernea & metabolic acidosis.
Specimen TypeBlood
Sample typeSerum
Minimum Volume0.5mL If requesting more than 10 tests please send an additional brown clotted serum sample.
Special PrecautionsNo special requirements
Stability1 week at 2 - 8°C
Turnaround TimeUrgent: 2 hours Inpatient: 4 hours Outpatient/ GP: 24 hours
LaboratoryYork and Scarborough
Reference IntervalWhen used as an anti-inflammatory: Adults: <350 mg/L Children: <280 mg/L
LimitationsLipaemic and icteric samples are not suitable for analysis. P-aminosalicylic acid, 2,5-dihydroxybenzoic acid and 2,5-dihydroxyphenylacetic acid were found to give falsely elevated results.
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