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Laboratory Medicine

Test Directory / Total Bilirubin

Total Bilirubin

Brown clotted serum, gel barrier or orange lithium heparin

TestTotal Bilirubin
Common AbbreviationsTBIL, BILI
ProfileLiver Function Test
Tube typeBrown clotted serum, gel barrier or orange lithium heparin
Clinical IndicationInvestigation and monitoring of jaundice, hepatocellular dysfunction (e.g. impaired conjugation of bilirubin) and haemolysis.
Specimen TypeBlood
Sample typeSerum
Minimum Volume0.5mL If requesting more than 10 tests please send an additional brown clotted serum sample.
Special PrecautionsSample tubes should be stored in the dark if not analysed immediately
Stability7 days at 2-8°C (stored in the dark)
Turnaround TimeUrgent: 2 hours Inpatient: 4 hours Outpatient/ GP: 24 hours
LaboratoryYork and Scarborough
Reference Interval Adults and children >14 days old: <21 umol/L (Recommended by Pathology Harmonisation Reference Group)
LimitationsHaemolysis may interfere with bilirubin measurement. In very rare cases gammopathy, especially monoclonal IgM (Waldenström’s macroglobulinaemia), may cause unreliable results. Hydroxocobalamin or Cyanokit (cyanide antidote) may cause interference.
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