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Laboratory Medicine

Test Directory / Coagulation factor VIII assay

Coagulation factor VIII assay

Citrated Plasma

TestCoagulation factor VIII assay
Common AbbreviationsFVIII
Profile Coagulation Screen added on the same sample
Clinical IndicationTo determine if the coagulation factor VIII is low or absent. Associated with reduced clot formation and bleeding. Coagulation factor levels may also be measured to monitor the level during therapy. Contact Consultant Haematologist for advice.
Specimen TypeBlood
Sample TypeCitrated Plasma
Minimum Volume2 x 3 mL (adult) 2 x 1 mL (paed) (citrated plasma must be filled to bottle line)
Special PrecautionsMust write type of replacement factor product if relevant. Must state if patient is on anticoagulants (DOAC, Warfarin, Heparin); known coagulation disorders; clincal symptoms (bleeding, bruising).
Stability4-6 hours
Turnaround Time4 hours (urgent) if requested via the haematology consultants. 3 weeks (routine)
LaboratoryYork Hospital
Reference IntervalReference range printed on final report.
LimitationsHaemolysis, gross lipaemia, high haematocrit may interfere with measurement. Over or under filled samples cannot be used due to ratio between blood and citrate
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