Laboratory Medicine

Test Directory / Anti-neutrophil cytoplasmic Antibody

Anti-neutrophil cytoplasmic Antibody

Brown clotted serum, gel barrier

Test	Anti-neutrophil cytoplasmic Antibody
Common Abbreviations	ANCA
Profile	Anti Myeloperoxidase antibody (MPO) and anti-Proteinase 3 antibody also performed along with ANCA
Clinical Indication	Rapidly progressive glomerular nephritis; pulmonary haemorrhage. Small vessel vasculitis.
Specimen Type	Blood
Sample Type	Serum
Minimum Volume	5 ml
Special Precautions	No special requirements
Stability	14 days
Turnaround Time	7 Days. Please note if result is required urgently, contact immunology laboratory directly (mon-fri, 8.30-5)
Laboratory	Hull Royal Infirmary, Anlaby Road, Hull HU3 2JZ
Reference Interval	Negative or positive (Plus staining pattern of cytoplasmic c-ANCA or perinuclear p-ANCA).
Limitations	The assay should not be performed on grossly haemolysed or grossly lipaemic samples.

Update for visitors

Visiting restrictions are in place at our hospitals to stop the spread of norovirus. These restrictions will be in place until further notice.

The following wards are closed to visitors:

York Hospital: Ward 29 and Ward 37.

There are four exceptions only to the restrictions. These are:

For patients who are receiving end of life care

Paediatric patients (babies and children)

Maternity care

The family carers of those with dementia

We understand these restrictions can be difficult when a loved one is unwell. The restrictions will be reviewed daily and lifted as soon as it is safe. Thank you for your understanding as we try to reduce the spread of norovirus in our hospitals.