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Laboratory Medicine

Test Directory / Double Stranded DNA antibody assay

Double Stranded DNA antibody assay

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TestDouble Stranded DNA antibody assay
Common AbbreviationsdsDNA
ProfileDouble stranded DNA antibodies are only performed if ANA is positive. Referred for Crithidia antibody if dsDNA assay is positive.
Clinical IndicationDouble stranded DNA antibodies are associated with SLE
Specimen TypeBlood
Sample TypeSerum
Minimum Volume5 ml
Special PrecautionsNo special requirements
Stability10 days
Turnaround Time7 days (turnaround time maybe longer if referred for confirmatory Crithidia test)
Reference IntervalNeg <27 IU/mL Intermediate 27-35 IU/mL Pos >35 IU/mL
LimitationsThe assay should not be performed on grossly haemolysed or grossly lipaemic samples. Only serum samples will be accepted
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