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Laboratory Medicine

Test Directory / LGI1 and CASPR2 Antibodies (VGKC-complex antibodies)

LGI1 and CASPR2 Antibodies (VGKC-complex antibodies)

Brown clotted serum, gel barrier

TestLGI1 and CASPR2 Antibodies (VGKC-complex antibodies)
Common Abbreviations
ProfileN/A
Clinical IndicationVGKC antibodies have recently been renamed VGKC-complex antibodies, as it is now recognised that the VGKCs are tightly complexed with other proteins and that the radioimmunoprecipitaion assay recognises the complexed proteins as well as the VGKCs themselves. The most common complex proteins discovered so far are LGI1 and CASPR2. However, as not all the complex proteins have been identified, we recommend testing for VGKC-complex antibodies as a first step.
Specimen TypeBlood
Sample TypeSerum
Minimum Volume1 mL
Special PrecautionsNo special requirements
StabilityContact Referral Laboratory
Turnaround Time3 weeks
LaboratoryNeurosciences Group Institute of Molecular Medicine John Radcliffe Hospital Headington Oxford OX3 9DS
Reference IntervalContact Referral Laboratory
LimitationsContact Referral Laboratory
IMG_3571

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