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Laboratory Medicine

Test Directory / Muscle specific tyrosine kinase

Muscle specific tyrosine kinase

Brown clotted serum, gel barrier

TestMuscle specific tyrosine kinase
Common AbbreviationsMUSK
ProfileN/A
Clinical IndicationMuscle specific tyrosine kinase (MUSK) is a surface membrane enzyme that is essential in aggregating Acetylcholine receptor during the development of the neuromuscular junction. Recent studies have shown that antibodies to Musk are present in 40% to 50% of patients with generalized Acetylcholine Receptor seronegative MG. Anti-Musk antibodies have not been found in patients with purely ocular myasthenia or in those with anti-acetylcholine receptor antibodies.
Specimen TypeBlood
Sample TypeSerum
Minimum Volume1 mL
Special PrecautionsNo special requirements
StabilityContact Referral Laboratory
Turnaround Time3 weeks
LaboratoryNeurosciences Group Institute of Molecular Medicine John Radcliffe Hospital Headington Oxford OX3 9DS
Reference IntervalContact Referral Laboratory
LimitationsContact Referral Laboratory
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