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Laboratory Medicine

Test Directory / Paraneoplastic Antibodies Also known as: Cereberal or Neuronal Antibodies

Paraneoplastic Antibodies Also known as: Cereberal or Neuronal Antibodies

Brown clotted serum, gel barrier

TestParaneoplastic Antibodies Also known as: Cereberal or Neuronal Antibodies
Common AbbreviationsAPUR
ProfileIncludes antibodies to Hu, Yo, and Ri. Ma1, Ma2, CV2, amphyphysin, Sox1, Tr, PCA2, Zic4 and Gephyrin by prior arrangement.
Clinical IndicationParaneoplastic disorders are characterized by the presence of neuronal autoantibodies in patient serum. The detection of these autoantibodies is useful for the clinician, as it suggests the presence of an underlying tumour. Tumours that have been known to initiate paraneoplastic disorders include small cell lung carcinoma (SCLC), thymoma, neuroblastoma, and breast, ovarian, and testicular cancers.
Specimen TypeBlood
Sample TypeSerum (CSF not required but can be tested)
Minimum Volume1 mL
Special PrecautionsNo special requirements
StabilityContact Referral Laboratory
Turnaround Time3 weeks
LaboratoryNeurosciences Group Institute of Molecular Medicine John Radcliffe Hospital Headington Oxford OX3 9DS
Reference IntervalContact Referral Laboratory
LimitationsContact Referral Laboratory
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