Laboratory Medicine

Test Directory / Phospholipase A2 Antibody

Phospholipase A2 Antibody

Brown clotted serum, gel barrier

Test	Phospholipase A2 Antibody
Common Abbreviations	PLA2R MPLA2R
Profile	N/A
Clinical Indication	Membranous glomerulonephritis presents with nephrotic syndrome or proteinuria and is identified on renal biopsy by epithelial IgG and C3 deposition. APLA2R antibody measurement may have a role in identifying primary from secondary membranous nephropathy and also in disease monitoring. However they should not be viewed as a replacemant for renal biopsy in the investigation of patients presenting with nephrotic syndrome.
Specimen Type	Blood
Sample Type	Serum
Minimum Volume	2 mL
Special Precautions	No special requirements
Stability	Contact Referral Laboratory
Turnaround Time	3 weeks
Laboratory	Immunology Department, Northern General Hospital, Sheffield
Reference Interval	Contact Referral Laboratory
Limitations	Contact Referral Laboratory

Update for visitors

Visiting restrictions are in place at our hospitals to stop the spread of norovirus. These restrictions will be in place until further notice.

The following wards are closed to visitors:

York Hospital: Ward 29 and Ward 37.

There are four exceptions only to the restrictions. These are:

For patients who are receiving end of life care

Paediatric patients (babies and children)

Maternity care

The family carers of those with dementia

We understand these restrictions can be difficult when a loved one is unwell. The restrictions will be reviewed daily and lifted as soon as it is safe. Thank you for your understanding as we try to reduce the spread of norovirus in our hospitals.