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Laboratory Medicine

Test Directory / Voltage gated Ca2+ Antibodies Also know as: Calcium channel antibodies, LEMS

Voltage gated Ca2+ Antibodies Also know as: Calcium channel antibodies, LEMS

Brown clotted serum, gel barrier

TestVoltage gated Ca2+ Antibodies Also know as: Calcium channel antibodies, LEMS
Common AbbreviationsVGCC
Profile
Clinical IndicationThe assay is positive in approximately 85% of patients with the Lambert Eaton myasthenic syndrome (with or without small cell lung carcinoma SCLC) and in about 30% of Cerebellar ataxia with SCLC. Calcium channel antibodies are rarely found in patients without myasthenic symptoms, except at low titre in a few cases with small cell lung cancer. This is because small cell lung cancers express this voltage gated calcium channel.
Specimen TypeBlood
Sample TypeSerum
Minimum Volume1 mL
Special PrecautionsNo special requirements
StabilityContact Referral Laboratory
Turnaround Time4 weeks
LaboratoryNeurosciences Group Institute of Molecular Medicine John Radcliffe Hospital Headington Oxford OX3 9DS
Reference IntervalContact Referral Laboratory
LimitationsContact Referral Laboratory
IMG_3801

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