Laboratory Medicine

Test Directory / Thiopurine Methyl Transferase

Thiopurine Methyl Transferase

EDTA

Test	Thiopurine Methyl Transferase
Common Abbreviations	TPMT
Profile	NA
Tube type	EDTA
Clinical Indication	Activity of TPMT exhibits genetic polymorphism within 1 in 10 caucasians having reduced activity. These patients are at risk of haematopoietic toxicity, myelosuppression and even death. Measuring TPMT activity enables appropriate dosing.
Specimen Type	Blood
Sample type	EDTA whole blood
Minimum Volume	4mL
Special Precautions	No special requirements
Stability	Contact Referral Laboratory
Turnaround Time	1 working day
Laboratory	City Hospital Birmingham B18 7QH 0121 507 5345
Reference Interval	Contact Referral Laboratory
Limitations	Contact Referral Laboratory
Notes

Update for visitors

Visiting restrictions are in place at our hospitals to stop the spread of norovirus. These restrictions will be in place until further notice.

The following wards are closed to visitors:

York Hospital: Ward 29 and Ward 37.

There are four exceptions only to the restrictions. These are:

For patients who are receiving end of life care

Paediatric patients (babies and children)

Maternity care

The family carers of those with dementia

We understand these restrictions can be difficult when a loved one is unwell. The restrictions will be reviewed daily and lifted as soon as it is safe. Thank you for your understanding as we try to reduce the spread of norovirus in our hospitals.