Laboratory Medicine
Test Directory / Thiopurine Methyl Transferase
Thiopurine Methyl Transferase
EDTA
| Test | Thiopurine Methyl Transferase |
|---|---|
| Common Abbreviations | TPMT |
| Profile | NA |
| Tube type | EDTA |
| Clinical Indication | Activity of TPMT exhibits genetic polymorphism within 1 in 10 caucasians having reduced activity. These patients are at risk of haematopoietic toxicity, myelosuppression and even death. Measuring TPMT activity enables appropriate dosing. |
| Specimen Type | Blood |
| Sample type | EDTA whole blood |
| Minimum Volume | 4mL |
| Special Precautions | No special requirements |
| Stability | Contact Referral Laboratory |
| Turnaround Time | 1 working day |
| Laboratory | City Hospital Birmingham B18 7QH 0121 507 5345 |
| Reference Interval | Contact Referral Laboratory |
| Limitations | Contact Referral Laboratory |
| Notes |
