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Laboratory Medicine

Test Directory / Beta-2-Microglobulin

Beta-2-Microglobulin

Brown clotted serum, gel barrier

TestBeta-2-Microglobulin
Common AbbreviationsB2M
ProfileNA
Tube typeBrown clotted serum, gel barrier
Clinical IndicationUsed as a tumour marker in the monitoring of myeloma, lymphoma and leukaemia. Raised levels in renal patients may indicate dialysis-related amyloidosis or transplant rejection. Less commonly, measurement of B2M in serum and urine may be used to distinguish between glomerular and tubular causes of proteinuria.
Specimen TypeBlood
Sample typeSerum
Minimum Volume0.5mL If requesting more than 10 tests please send an additional brown clotted serum sample.
Special PrecautionsNo special requirements
Stability3 days at 2-25°C
Turnaround TimeInpatient: 24 hours Outpatient/ GP: 24 hours
LaboratoryYork
Reference Interval Adults: 0.8 - 2.2 mg/L - New range as of 03/04/18 (Quoted by manufacturer)
LimitationsRaised levels of beta 2 microglobulin may be observed in any condition where there is increased cell turnover or immune activity e.g. CMV and HIV infection, inflammatory and autoimmune disorders.
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