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Laboratory Medicine

Test Directory / Antithrombin Assay

Antithrombin Assay

Citrated Plasma (& Brown clotted serum, gel barrier if part of a thrombophilia screen)

TestAntithrombin Assay
Common AbbreviationsAT
ProfileThrombophilia Screen Antithrombin (AT), Protein C (PC), Protein S (PS) Thrombin Time (TT), Factor V Leiden (FVL), Prothrombin Gene Mutation (F2G), Lupus Inhibitor (LIS), Anticardiolipin (ACA), B2 Glyocprotein (B2GLY), Coagulation Screen (CLS)
Clinical IndicationUsed in conjuction with other tests (within the thrombophilia screen) to screen for underlying causes of venous thromboembolism (VTE).
Specimen TypeBlood
Sample TypeCitrated Plasma & Brown clotted serum, gel barrier
Minimum Volume1 x 3mL (adult) 1 x 1mL (paed) (Thrombophlia Screen requires:3 x 3mL (adult) 4 x 1mL (paed) and 1 x brown serum for ACA & B2GLY (citrated plasma must be filled to bottle line)
Special PrecautionsTested not suitable if on anticoagulants or within the post thrombotic period
Stability24 hours
Turnaround Time3 - 6 weeks
LaboratoryYork Hospital
Reference IntervalReference range printed on final report.
LimitationsHaemolysis, gross lipaemia, high haematocrit may interfere with measurement. Over or under filled samples cannot be used due to ratio between blood and citrate
Additional Information
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