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Laboratory Medicine

Test Directory / Lupus inhibitor screen

Lupus inhibitor screen

Citrated Plasma & Brown clotted serum, gel barrier

TestLupus inhibitor screen
Common AbbreviationsLIS, LUP, lupus anticoagulant
ProfileMust be requested with an anticardiolipin (ACA) and B2 Glycoprotein (B2GLY) or Thrombophilia Screen Antithrombin (AT), Protein C (PC), Protein S (PS) Thrombin Time (TCT), Factor V Leiden (FVL), Prothrombin Gene Mutation (F2G), Lupus Inhibitor (LIS), Anticardiolipin (ACA), B 2 Glycoprotein (B2GLY), Coagulation Screen (CLS)
Clinical IndicationLupus anticoagulant testing is used to help determine the cause of an unexplained thrombosis, recurrent foetal loss, or a prolonged aPTT test.
Specimen TypeBlood
Sample TypeCitrated Plasma & Brown clotted serum, gel barrier
Minimum Volume2 x 3mL (adult) 2 x 1mL (paed) plus brown tube for ACA and B2Gly (Thrombophlia Screen requires:3 x 3mL (adult) 4 x 1mL (paed) and 1 x 0.5 - 1.0 mL brown serum for ACA & B2GLY (citrated plasma must be filled to bottle line)
Special PrecautionsCannot be perform if on DOAC's and Warfarin.
Stability4-6 hours
Turnaround TimeUrgent samples can be completed in 4 hours if requested via the haematology consultants. 3 - 6 weeks (routine)
LaboratoryYork Hospital
Reference IntervalReference range printed on final report.
LimitationsHaemolysis, gross lipaemia, high haematocrit may interfere with measurement. Over or under filled samples cannot be used due to ratio between blood and citrate
Additional Information
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