Laboratory Medicine

Test Directory / Liver Antibodies (including gastric parietal cell, liver kidney microsomal, smooth muscle and mitochondrial antibodies)

Liver Antibodies (including gastric parietal cell, liver kidney microsomal, smooth muscle and mitochondrial antibodies)

Brown clotted serum, gel barrier

Test	Liver Antibodies (including gastric parietal cell, liver kidney microsomal, smooth muscle and mitochondrial antibodies)
Common Abbreviations	LABS
Profile	Liver antibody screening also includes ANA. Liver Immunoblot performed to confirm mitochondrial/LKM positivity
Clinical Indication	Suspicion of autoimmune liver diseases including Primary Billiary Cholangitis (PBC) and Autoimmune hepatitis. Gastric perietal cell antibodies can be present in Pernicious anaemia
Specimen Type	Blood
Sample Type	Serum
Minimum Volume	5 ml
Special Precautions	No special requirements
Stability	Contact Referral Laboratory
Turnaround Time	21 Days
Laboratory	Hull Royal Infirmary, Anlaby Road, Hull HU3 2JZ
Reference Interval	Negative or positive (titres) Confirmation by immunoblot
Limitations	The assay should not be performed on grossly haemolysed or grossly lipaemic samples. Only serum samples will be accepted

Update for visitors

Visiting restrictions are in place at our hospitals to stop the spread of norovirus. These restrictions will be in place until further notice.

The following wards are closed to visitors:

York Hospital: Ward 29 and Ward 37.

There are four exceptions only to the restrictions. These are:

For patients who are receiving end of life care

Paediatric patients (babies and children)

Maternity care

The family carers of those with dementia

We understand these restrictions can be difficult when a loved one is unwell. The restrictions will be reviewed daily and lifted as soon as it is safe. Thank you for your understanding as we try to reduce the spread of norovirus in our hospitals.