Laboratory Medicine
Test Directory / Anti-GAD
Anti-GAD
Brown clotted serum, gel barrier
| Test | Anti-GAD | 
|---|---|
| Common Abbreviations | GAD | 
| Profile | N/A | 
| Clinical Indication | Antibodies to glutamic acid decarboxylase (anti-GAD) are reliable serological markers of Insulin-dependent diabetes mellitus. Anti-GAD antibodies in high titre are associated with the stiff-person syndrome (60% sensitivity), a rare neurological disease characterised by muscle rigidity and spasms. | 
| Specimen Type | Blood | 
| Sample Type | Serum | 
| Minimum Volume | 1 mL | 
| Special Precautions | No special requirements | 
| Stability | Contact Referral Laboratory | 
| Turnaround Time | 3 weeks | 
| Laboratory | Immunology Laboratory, Oxford University Hospitals NHSFT | 
| Reference Interval | Contact Referral Laboratory | 
| Limitations | Contact Referral Laboratory | 






