Laboratory Medicine
General Information / Advice for requesters - Clinical Biochemistry
Please find information by clicking on the links below:
Advice Regarding Test Requesting and Result Interpretation:
ALLERGY TESTING - How to diagnose allergy in adults in primary care
B12 - see HAEMATINICS
BIOTIN- Biotin interference in Roche-manufactured immunoassays
BNP - Use of natriuretic peptides in the management of suspected heart failure
CALPROTECTIN
- The York faecal calprotectin care pathway for GPs
- Faecal calprotectin guidance for patients being managed in secondary care
CORTISOL - Diagnosis of Cushings Syndrome
CHLORIDE – Guidance for interpreting chloride results
CREATINE KINASE - Causes of Elevated CK
CRP - See INFLAMMATORY MARKERS
CUSHINGS SYNDROME - See CORTISOL
DIABETES - see HBA1C
ESR - See INFLAMMATORY MARKERS
ESTRADIOL – See OESTRADIOL
FAECAL CALPROTECTIN - See CALPROTECTIN
FERRITIN (high) - Investigation of elevated ferritin *Updated Aug 2022*
FERRITIN (low) See HAEMATINICS
FOLATE - See HAEMATINCS
FREE LIGHT CHAINS – Guidance for interpreting free light chain results
FSH - Menopause investigation and laboratory testing
HAEMATINICS - Guidance for primary care on interpretation of haematinics (B12, folate and ferritin)
HBA1C (diagnosis of diabetes) – Guidance for when HbA1c is not suitable for diagnosis of diabetes
HBA1C (monitoring of diabetes) – Guidance for when HbA1c is not suitable for monitoring diabetes
HEART FAILURE - See BNP
HYPERKALAEMIA - See POTASSIUM
HYPONATRAEMIA - See SODIUM
HYPOMAGNESAEMIA - See MAGNESIUM
HYPOPHOSPHATAEMIA - See PHOSPHATE
IMMUNOGLOBULINS - Guidance for investigation of low immunoglobulins
INFLAMMATORY MARKERS – Guidance for which test to use and when
LIVER BLOOD TESTS / LIVER DISEASE -
- Guidance for primary care on liver disease and liver blood tests
- Reference Ranges for Liver Function Tests in Pregnancy
MAGNESIUM - Guidance for assessment and management of hypomagnesaemia in primary care
MENOPAUSE - See FSH
METANEPHRINES (Urine) – Investigation of suspected phaeochromocytoma using 24h urine metanephrines
MYELOMA/MGUS - See PARAPROTEINS
OSMOLALITY (Urine) - Guidance for investigation of polyuria / polydipsia *Updated Oct 22*
OESTRADIOL – Interpreting serum oestradiol levels
PARAPROTEINS - Management of patients with paraprotein
PHOSPHATE -
Information for Primary Care: Management of Hypophosphataemia **new document Feb 2023**
Renal Tubular Reabsorption of Phosphate
POTASSIUM -
- Investigating and management of hyperkalaemia (high potassium) in primary care (adults)
- Investigating and management of hypokalaemia (low potassium) in primary care (adults)
- Top tips for avoiding haemolysis
- Hyperkalaemia due to DELAYED CENTRIFUGATION
- To enquire about obtaining a centrifuge for your surgery, please contact Carl Burkinshaw, Biochemistry Operational Manager (York and Scarborough): 01723 342028, carl.burkinshaw@york.nhs.uk
POLYURIA- see OSMOLALITY (Urine)
PROLACTIN - Investigation of hyperprolactinaemia
PV - See INFLAMMATORY MARKERS
Renal Tubular Reabsorption of Phosphate - See PHOSPHATE
SODIUM - Investigation and management of hyponatraemia in primary care (adults)
THERAPEUTIC DRUGS - Sampling requirements for commonly requested therapeutic drugs
THYROID FUNCTION TESTS - Guidance for requesting and interpreting thyroid function tests (TFTs)
TRACE ELEMENTS (ZINC, SELENIUM, COPPER) - A guide to requesting trace elements for adults in primary care
TROPONIN - Troponin testing in primary care
Information Regarding Service Delivery
2018 01: REPORTING PROBLEMS
Procedure for recording and reporting sample quality problems
2019 03: INSULIN LIKE GROWTH FACTOR (IGF-1)
2019 04: CKD-EPI
Use of the CKD-EPI equation (NICE guideline 182)
Sample Collection and Testing Protocols
Urine Collection Procedure for 24 hour urine
Overnight Dexamethasone Suppression Test
Clinical Biochemistry Archived User Communications
Web Page 26 Last Updated: 22/03/2023
Advice for Requesters - Cervical Cytology
Advice for Requestors - Immunology
Advice for Requesters- Microbiology
Advice for requesters - Clinical Biochemistry
Transportation of Samples and Postage
High Risk/Danger of Infection Samples
Request form and specimen labelling