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Laboratory Medicine

General Information / Advice for requesters - Clinical Biochemistry

Please find information by clicking on the links below:

Advice Regarding Test Requesting and Result Interpretation:

ALLERGY TESTING - How to diagnose allergy in adults in primary care - **New document June 2020**

B12 - see HAEMATINICS

BNP - Use of natriuretic peptides in the management of suspected heart failure

CALPROTECTIN

- The York faecal calprotectin care pathway for GPs

 - Cut-offs for patients in secondary care

CORTISOL - Diagnosis of Cushings Syndrome

CREATINE KINASE - Causes of Elevated CK  **Updated Aug 2021**

CRP - See INFLAMMATORY MARKERS

CUSHINGS SYNDROME - See CORTISOL

DIABETES - see HBA1C

ESR - See INFLAMMATORY MARKERS

ESTRADIOL – See OESTRADIOL

FAECAL CALPROTECTIN - See CALPROTECTIN

FERRITIN (high) - Investigation of elevated ferritin

FERRITIN (low) See HAEMATINICS

FOLATE - See HAEMATINCS

FSH - Menopause investigation and laboratory testing

HAEMATINICS - Guidance for primary care on interpretation of haematinics (B12, folate and ferritin)  **Updated Aug 2021**

HBA1C (diagnosis of diabetes)Guidance for when HbA1c is not suitable for diagnosis of diabetes

HBA1C (monitoring of diabetes)Guidance for when HbA1c is not suitable for monitoring diabetes

HEART FAILURE - See BNP

HYPERKALAEMIA - See POTASSIUM

HYPONATRAEMIA - See SODIUM

HYPOMAGNESAEMIA - See MAGNESIUM

INFLAMMATORY MARKERS – Guidance for which test to use and when

LIVER BLOOD TESTS / LIVER DISEASE - Guidance for primary care on liver disease and liver blood tests **Updated June 21**

MAGNESIUM - Guidance for assessment and management of hypomagnesaemia in primary care

MENOPAUSE - See FSH

MYELOMA/MGUS - See PARAPROTEINS

OSMOLALITY (Urine) - Guidance for investigation of polyuria / polydipsia

OESTRADIOLInterpreting serum oestradiol levels

PARAPROTEINS - Management of patients with paraprotein bands in primary care

PHOSPHATE - Renal Tubular Reabsorption of Phosphate

POTASSIUM -

- Investigating and management of hyperkalaemia in primary care (adults) *Updated April 2021*

- Top tips for avoiding haemolysis

- Hyperkalaemia due to DELAYED CENTRIFUGATION

- To enquire about obtaining a centrifuge for your surgery, please contact Carl Burkinshaw, Biochemistry Operational Manager (York and Scarborough): 01723 342028, carl.burkinshaw@york.nhs.uk

POLYURIA- see OSMOLALITY (Urine)

PROLACTIN - Investigation of hyperprolactinaemia

PV - See INFLAMMATORY MARKERS

Renal Tubular Reabsorption of Phosphate - See PHOSPHATE

SODIUM - Investigation and management of hyponatraemia in primary care (adults)

THERAPEUTIC DRUGS - Sampling requirements for commonly requested therapeutic drugs *Updated Nov 2020*

THYROID FUNCTION TESTS - Guidance for requesting and interpreting thyroid function tests (TFTs) *Updated Feb 2021*

TRACE ELEMENTS (ZINC, SELENIUM, COPPER) - A guide to requesting trace elements for adults in primary care – *NEW March 2021*

TROPONIN - Troponin testing in primary care

Information Regarding Service Delivery

2018 01: REPORTING PROBLEMS

Procedure for recording and reporting sample quality problems

2019 02:  TEST INTERFERENCE

Biotin interference in Roche-manufactured immunoassays

2019 03: INSULIN LIKE GROWTH FACTOR (IGF-1)

Reference Ranges

2019 04: CKD-EPI

Use of the CKD-EPI equation (NICE guideline 182)

 

Sample Collection and Testing Protocols

Aldosterone Renin Ratio

Urine Collection Procedure for 24 hour urine

Glucose Tolerance Test

Short Synacthen Test

Overnight Dexamethasone Suppression Test

Clinical Biochemistry Archived User Communications 

Archived Communications


Web Page 26 Last Updated: 23/08/2021

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