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Laboratory Medicine

General Information / Advice for requesters - Clinical Biochemistry

Please find information by clicking on the links below:

Advice Regarding Test Requesting and Result Interpretation:

ALLERGY TESTING - How to diagnose allergy in adults in primary care *Updated Dec 2021*

B12 - see HAEMATINICS

BIOTIN- Biotin interference in Roche-manufactured immunoassays *Updated Nov 2021*

BNP - Use of natriuretic peptides in the management of suspected heart failure

CALPROTECTIN

- The York faecal calprotectin care pathway for GPs

 - Faecal calprotectin guidance for patients being managed in secondary care *Updated Nov 2021*

CORTISOL - Diagnosis of Cushings Syndrome

CHLORIDE – Guidance for interpreting chloride results *New Document 2022*

CREATINE KINASE - Causes of Elevated CK  *Updated Aug 2021*

CRP - See INFLAMMATORY MARKERS

CUSHINGS SYNDROME - See CORTISOL

DIABETES - see HBA1C

ESR - See INFLAMMATORY MARKERS

ESTRADIOL – See OESTRADIOL

FAECAL CALPROTECTIN - See CALPROTECTIN

FERRITIN (high) - Investigation of elevated ferritin

FERRITIN (low) See HAEMATINICS

FOLATE - See HAEMATINCS

FREE LIGHT CHAINS – Guidance for interpreting free light chain results *New Nov 2021*

FSH - Menopause investigation and laboratory testing

HAEMATINICS - Guidance for primary care on interpretation of haematinics (B12, folate and ferritin)  *Updated Aug 2021*

HBA1C (diagnosis of diabetes)Guidance for when HbA1c is not suitable for diagnosis of diabetes

HBA1C (monitoring of diabetes)Guidance for when HbA1c is not suitable for monitoring diabetes

HEART FAILURE - See BNP

HYPERKALAEMIA - See POTASSIUM

HYPONATRAEMIA - See SODIUM

HYPOMAGNESAEMIA - See MAGNESIUM

IMMUNOGLOBULINS  - Guidance for investigation of low immunoglobulins *New Document October 2021*

INFLAMMATORY MARKERS – Guidance for which test to use and when * Updated Feb 2022*

LIVER BLOOD TESTS / LIVER DISEASE - Guidance for primary care on liver disease and liver blood tests *Updated Nov 21*

MAGNESIUM - Guidance for assessment and management of hypomagnesaemia in primary care *Updated Dec 2021*

MENOPAUSE - See FSH

METANEPHRINES (Urine) – Investigation of suspected phaeochromocytoma using 24h urine metanephrines - *New Nov 2021*

MYELOMA/MGUS - See PARAPROTEINS

OSMOLALITY (Urine) - Guidance for investigation of polyuria / polydipsia

OESTRADIOLInterpreting serum oestradiol levels

PARAPROTEINS - Management of patients with paraprotein *Updated March 2022*

PHOSPHATE - Renal Tubular Reabsorption of Phosphate *Updated March 2022*

POTASSIUM -

- Investigating and management of hyperkalaemia (high potassium) in primary care (adults)

- Investigating and management of hypokalaemia (low potassium) in primary care (adults) * New document - April 2022*

- Top tips for avoiding haemolysis

- Hyperkalaemia due to DELAYED CENTRIFUGATION

- To enquire about obtaining a centrifuge for your surgery, please contact Carl Burkinshaw, Biochemistry Operational Manager (York and Scarborough): 01723 342028, carl.burkinshaw@york.nhs.uk

POLYURIA- see OSMOLALITY (Urine)

PROLACTIN - Investigation of hyperprolactinaemia

PV - See INFLAMMATORY MARKERS

Renal Tubular Reabsorption of Phosphate - See PHOSPHATE

SODIUM - Investigation and management of hyponatraemia in primary care (adults)

THERAPEUTIC DRUGS - Sampling requirements for commonly requested therapeutic drugs

THYROID FUNCTION TESTS - Guidance for requesting and interpreting thyroid function tests (TFTs)

TRACE ELEMENTS (ZINC, SELENIUM, COPPER) - A guide to requesting trace elements for adults in primary care – *NEW March 2021*

TROPONIN - Troponin testing in primary care

Information Regarding Service Delivery

2018 01: REPORTING PROBLEMS

Procedure for recording and reporting sample quality problems

2019 03: INSULIN LIKE GROWTH FACTOR (IGF-1)

Reference Ranges

2019 04: CKD-EPI

Use of the CKD-EPI equation (NICE guideline 182)

 

Sample Collection and Testing Protocols

Aldosterone Renin Ratio

Urine Collection Procedure for 24 hour urine *Updated Nov 2021*

Glucose Tolerance Test *Updated March 2022*

Short Synacthen Test

Overnight Dexamethasone Suppression Test

Clinical Biochemistry Archived User Communications 

Archived Communications


Web Page 26 Last Updated: 25/04/2022

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